bioinformatic analysis of usp2 expression (Human Protein Atlas)
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Human Protein Atlas
bioinformatic analysis of usp2 expression
Bioinformatic Analysis Of Usp2 Expression, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bioinformatic+analysis+of+usp2+expression/bioinformatic+analysis+of+usp2+expression/pm37670038-348-4-15
Average 90 stars, based on 1 article reviews
Bioinformatic Analysis Of Usp2 Expression, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bioinformatic+analysis+of+usp2+expression/bioinformatic+analysis+of+usp2+expression/pm37670038-348-4-15
Average 90 stars, based on 1 article reviews
bioinformatic analysis of usp2 expression - by Bioz Stars,
2026-10
90/100 stars
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Expressing:Article Title: USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1. Article Snippet: The abnormal upregulation of programmed death ligand-1 (PD-L1) on tumor cells impedes T-cell mediated cytotoxicity through PD-1 engagement, and further exploring the mechanisms regulation of PD-L1 in cancers may enhance the clinical efficacy of PD-L1 blockade.. Here, using single-guide RNAs (sgRNAs) screening system, we identify ubiquitin-specific processing protease 2 (USP2) as a novel regulator of PD-L1 stabilization for tumor immune evasion.. USP2 directly interacts with and increases PD-L1 abundance in colorectal and prostate cancer cells. |